Season 04, Episode 03 — “Uprising”
May fights for her life as her illness worsens and Simmons and Dr. Radcliffe try to save her. Also: Coulson, Mack and Fitz attempt to thwart a rogue group looking to end Inhuman Registration.
Phil Coulson (Clark Gregg, reprising his role from “The Avengers” and “Iron Man” ) heads an elite team of fellow agents with the worldwide law-enforcement organization known as SHIELD (Strategic Homeland Intervention Enforcement and Logistics Division), as they investigate strange occurrences around the globe. Its members — each of whom brings a specialty to the group — work with Coulson to protect those who cannot protect themselves from extraordinary and inconceivable threats, including a formidable group known as Hydra.